What must evidence-based guidelines be based on?

Evidence-based guidelines are fundamentally grounded in the most reliable and relevant research evidence available. This ensures that guidelines reflect the latest findings, methodologies, and outcomes from high-quality studies, including systematic reviews and meta-analyses. Utilizing up-to-date and rigorous research while developing guidelines helps provide recommendations that are effective, applicable, and beneficial for patient care.

Reliance on outdated research or solely on consensus among experts does not guarantee that the recommendations are effective or based on the most credible and current data. Similarly, local practice experiences, while valuable, can sometimes be idiosyncratic and not universally applicable. Thus, a foundation in the latest and most reliable evidence is critical in ensuring that guidelines can effectively improve patient outcomes and practice standards.